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overview Aron S. Buchman, MD, is a professor in the Department of Neurological Sciences at Rush University Medical Center in Chicago. Buchman received the degree of bachelor of science, cum laude, from Loyola University of Chicago in 1977. He was a Patinkin Fellow and spent 1979-80 studying medical ethics in Israel at the Regensberg Institute. He earned his doctorate in medicine from Chicago Medical School/University of Health Sciences in 1982. Following an internship in internal medicine at Brookdale Hospital in New York, Buchman returned to Rush for residency training in neurology and a fellowship in movement disorders and clinical neuropharmacology, which he completed in 1987. Buchman received additional fellowship training in clinical electrophysiology and neuromuscular diseases at the University of British Columbia and Vancouver General Hospital in 1987-88. Buchman received board certification in neurology in 1988 and from the American Board of Electrodiagnostic Medicine in 1989. He received added certification in clinical neurophysiology in 1994. Buchman served as director of the EMG Laboratory at Rush from 1988 to 1996 and acting director of the Section on Neuromuscular Diseases in 1997. He received a career development award from the NINDS/NIH from 1994-99 for his work that investigated motor control and motor unit recruitment. Buchman was a research fellow at the NeuroMuscular Research Center at Boston University from 1992-95. He was a visiting scientist in the Department of Applied Mathematics at the Weizmann Institute of Science from 1995-97. Buchman’s research interests include the effects of aging on the motor system. More recently his research has focused on identifying the structural basis of clinical frailty in older persons, exploring the pathologic indices linking risk factors to the development of frailty so as to provide a conceptual basis for the development and testing of interventions to reduce the burden of this common syndrome in older adults. My Scopus ID is 7101625478. My NIH COMMONS name is ABUCHMAN.
Person ID 349048
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Concept Receptors, Complement 3b
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Academic Article Cerebrovascular disease pathology and parkinsonian signs in old age.
Academic Article GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy.
Academic Article Effect of a purpose in life on risk of incident Alzheimer disease and mild cognitive impairment in community-dwelling older persons.
Academic Article Cognitive function is associated with risk aversion in community-based older persons.
Academic Article Quantification of the fragmentation of rest-activity patterns in elderly individuals using a state transition analysis.
Academic Article Increased fragmentation of rest-activity patterns is associated with a characteristic pattern of cognitive impairment in older individuals.
Academic Article Cognitive function is associated with the development of mobility impairments in community-dwelling elders.
Academic Article Sex difference in daily rhythms of clock gene expression in the aged human cerebral cortex.
Academic Article The APOE epsilon4 allele is associated with incident mild cognitive impairment among community-dwelling older persons.
Academic Article A common polymorphism near PER1 and the timing of human behavioral rhythms.
Academic Article Purpose in life is associated with mortality among community-dwelling older persons.
Academic Article Cellular, synaptic, and biochemical features of resilient cognition in Alzheimer's disease.
Academic Article Mixed pathology is more likely in black than white decedents with Alzheimer dementia.
Academic Article Regional Neocortical Gray Matter Structure and Sleep Fragmentation in Older Adults.
Academic Article Association of brain pathology with the progression of frailty in older adults.
Academic Article Purpose in life is associated with a reduced risk of incident disability among community-dwelling older persons.
Academic Article Motoric cognitive risk syndrome: multicountry prevalence and dementia risk.
Academic Article Lewy bodies and olfactory dysfunction in old age.
Academic Article Motoric cognitive risk syndrome: Multicenter incidence study.
Academic Article Frailty is associated with incident Alzheimer's disease and cognitive decline in the elderly.
Academic Article Pulmonary function, muscle strength, and incident mobility disability in elders.
Academic Article Association of Parkinson disease risk loci with mild parkinsonian signs in older persons.
Academic Article Relation of genomic variants for Alzheimer disease dementia to common neuropathologies.
Academic Article The Rush Memory and Aging Project: study design and baseline characteristics of the study cohort.
Academic Article Association of muscle strength with the risk of Alzheimer disease and the rate of cognitive decline in community-dwelling older persons.
Academic Article Harm avoidance and disability in old age.
Academic Article Loss of motor function in preclinical Alzheimer's disease.
Academic Article Association between life space and risk of mortality in advanced age.
Academic Article Suprachiasmatic neuron numbers and rest-activity circadian rhythms in older humans.
Academic Article Association of cognition with temporal discounting in community based older persons.
Academic Article GBA mutations increase risk for Lewy body disease with and without Alzheimer disease pathology.
Academic Article Parkinsonism in Older Adults and Its Association With Adverse Health Outcomes and Neuropathology.
Academic Article Correlates of life space in a volunteer cohort of older adults.
Academic Article CR1 is associated with amyloid plaque burden and age-related cognitive decline.
Academic Article Locus coeruleus neuron density and parkinsonism in older adults without Parkinson's disease.
Academic Article Higher brain BDNF gene expression is associated with slower cognitive decline in older adults.
Academic Article Vibratory thresholds and mobility in older persons.
Academic Article APOE e4 increases risk for dementia in pure synucleinopathies.
Academic Article Temporal course and pathologic basis of unawareness of memory loss in dementia.
Academic Article Odor identification and progression of parkinsonian signs in older persons.
Academic Article Life space and risk of Alzheimer disease, mild cognitive impairment, and cognitive decline in old age.
Academic Article A genome-wide association study of aging.
Academic Article Total daily activity declines more rapidly with increasing age in older adults.
Academic Article Common variants in DRD2 are associated with sleep duration: the CARe consortium.
Academic Article Harm avoidance and cerebral infarction.
Academic Article Transition Between the Timed up and Go Turn to Sit Subtasks: Is Timing Everything?
Academic Article Body mass index in older persons is associated with Alzheimer disease pathology.
Academic Article The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.
Academic Article Loneliness and the rate of motor decline in old age: the Rush Memory and Aging Project, a community-based cohort study.
Academic Article Visuoperceptual repetition priming and progression of parkinsonian signs in aging.
Academic Article APOE and cerebral amyloid angiopathy in community-dwelling older persons.
Academic Article The Role of MAPT Haplotype H2 and Isoform 1N/4R in Parkinsonism of Older Adults.
Academic Article Association between performance on Timed Up and Go subtasks and mild cognitive impairment: further insights into the links between cognitive and motor function.
Academic Article Irregular 24-hour activity rhythms and the metabolic syndrome in older adults.
Academic Article Association between late-life social activity and motor decline in older adults.
Academic Article Physical frailty in older persons is associated with Alzheimer disease pathology.
Academic Article Physical activity, motor function, and white matter hyperintensity burden in healthy older adults.
Academic Article Change in frailty and risk of death in older persons.
Academic Article Lower extremity motor function and disability in mild cognitive impairment.
Academic Article Total daily physical activity and the risk of AD and cognitive decline in older adults.
Academic Article What links gait speed and MCI with dementia? A fresh look at the association between motor and cognitive function.
Academic Article Medial plantar nerve testing facilitates identification of polyneuropathy.
Academic Article Respiratory muscle strength predicts decline in mobility in older persons.
Academic Article Pulmonary function, muscle strength and mortality in old age.
Academic Article Eosinophilia, myositis, and myasthenia gravis associated with a thymoma.
Academic Article Hemiparkinsonism with hemiatrophy.
Academic Article Physical activity and motor decline in older persons.
Academic Article Risk factors for progression in Parkinson's disease.
Academic Article Incident parkinsonism in older adults without Parkinson disease.
Academic Article Bromocriptine-induced myoclonus.
Academic Article Change in body mass index and risk of incident Alzheimer disease.
Academic Article Recovery following the "locked-in" syndrome.
Academic Article Effect of age and gender in the control of elbow flexion movements.
Academic Article Genetic susceptibility for ischemic infarction and arteriolosclerosis based on neuropathologic evaluations.
Academic Article Sleep Fragmentation and the Risk of Incident Alzheimer's Disease and Cognitive Decline in Older Persons.
Academic Article Ex vivo MRI transverse relaxation in community based older persons with and without Alzheimer's dementia.
Academic Article Urinary Incontinence, Incident Parkinsonism, and Parkinson's Disease Pathology in Older Adults.
Academic Article A translational approach to capture gait signatures of neurological disorders in mice and humans.
Academic Article Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.
Academic Article Sleep fragmentation and Parkinson's disease pathology in older adults without Parkinson's disease.
Academic Article Association Between Brain Gene Expression, DNA Methylation, and Alteration of Ex Vivo Magnetic Resonance Imaging Transverse Relaxation in Late-Life Cognitive Decline.
Academic Article Drosophila p53 is a structural and functional homolog of the tumor suppressor p53.
Academic Article Obstetrical brachial palsy: Pathogenesis, risk factors & prevention
Academic Article APOE e2e4 genotype, incident AD and MCI, cognitive decline, and AD pathology in older adults.
Academic Article Targeted brain proteomics uncover multiple pathways to Alzheimer's dementia.
Academic Article Seasonal plasticity of cognition and related biological measures in adults with and without Alzheimer disease: Analysis of multiple cohorts.
Academic Article Dietary Patterns and Self-reported Incident Disability in Older Adults.
Academic Article APOE genotypes as a risk factor for age-dependent accumulation of cerebrovascular disease in older adults.
Academic Article The transition between turning and sitting in patients with Parkinson's disease: A wearable device detects an unexpected sequence of events.
Academic Article Spinal motor neurons and motor function in older adults.
Academic Article Physical activity, common brain pathologies, and cognition in community-dwelling older adults.
Academic Article Disentangling the genetics of lean mass.
Academic Article MIND Diet Associated with Reduced Incidence and Delayed Progression of ParkinsonismA in Old Age.
Academic Article Hippocampal gene expression patterns linked to late-life physical activity oppose age and AD-related transcriptional decline.
Academic Article Incident Mobility Disability, Mild Cognitive Impairment, and Mortality in Community-Dwelling Older Adults.
Academic Article Progressive parkinsonism in older adults is related to the burden of mixed brain pathologies.
Academic Article Total Daily Physical Activity and the Risk of Parkinsonism in Community-Dwelling Older Adults.
Academic Article Expanding instrumented gait testing in the community setting: A portable, depth-sensing camera captures joint motion in older adults.
Academic Article Antiphospholipid Antibodies: Cognitive and Motor Decline, Neuroimaging and Neuropathology.
Academic Article Different Combinations of Mobility Metrics Derived From a Wearable Sensor Are Associated With Distinct Health Outcomes in Older Adults.
Academic Article Quantitative mobility metrics from a wearable sensor predict incident parkinsonism in older adults.
Academic Article Cognition may link cortical IGFBP5 levels with motor function in older adults.
Academic Article Neocortical Lewy bodies are associated with impaired odor identification in community-dwelling elders without clinical PD.
Academic Article Genetic risk for Alzheimer's dementia predicts motor deficits through multi-omic systems in older adults.
Academic Article Interaction between the progression of Alzheimer's disease and fractal degradation.
Academic Article More random motor activity fluctuations predict incident frailty, disability, and mortality.
Academic Article What happens before the first step? A New Approach to Quantifying Gait Initiation Using a Wearable Sensor.
Academic Article Sleep fragmentation, microglial aging, and cognitive impairment in adults with and without Alzheimer's dementia.
Academic Article Total daily physical activity, brain pathologies, and parkinsonism in older adults.
Academic Article Human Brain and Serum Advanced Glycation End Products are Highly Correlated: Preliminary Results of Their Role in Alzheimer Disease and Type 2 Diabetes.
Academic Article Associations Between Cardiovascular Risk, Structural Brain Changes, and Cognitive Decline.
Academic Article Dietary antioxidants associated with slower progression of parkinsonian signs in older adults.
Academic Article Fragmentation of Rest/Activity Patterns in Community-Based Elderly Individuals Predicts Incident Heart Failure.
Academic Article Person-Specific Contributions of Brain Pathologies to Progressive Parkinsonism in Older Adults.
Academic Article Brain pathologies are associated with both the rate and variability of declining motor function in older adults.
Academic Article Association of Cardiovascular Risk Burden With Risk and Progression of Disability: Mediating Role of Cardiovascular Disease and Cognitive Decline.
Academic Article Representation of Older Latinxs in Cohort Studies at the Rush Alzheimer's Disease Center.
Academic Article Automatic Quantification of Tandem Walking Using a Wearable Device: New Insights Into Dynamic Balance and Mobility in Older Adults.
Academic Article Semiautomatic morphometric analysis of skeletal muscle obtained by needle biopsy in older adults.
Academic Article Bayesian Genome-wide TWAS Method to Leverage both cis- and trans-eQTL Information through Summary Statistics.
Academic Article Neuropathologic burden and the degree of frailty in relation to global cognition and dementia.
Academic Article Association of Heel Bone Mineral Density With Incident Disability and Mortality in Community-Dwelling Older Adults.
Academic Article Association of Low Systolic Blood Pressure with Postmortem Amyloid-? and Tau.
Academic Article Deterioration in Motor Function Over Time in Older Adults With Type 2 Diabetes is Associated with Accelerated Cognitive Decline.
Academic Article Genome-wide meta-analysis of muscle weakness identifies 15 susceptibility loci in older men and women.
Academic Article Motor function is the primary driver of the associations of sarcopenia and physical frailty with adverse health outcomes in community-dwelling older adults.
Academic Article Incident mobility disability, parkinsonism, and mortality in community-dwelling older adults.
Academic Article Quantitative mobility measures complement the MDS-UPDRS for characterization of Parkinson's disease heterogeneity.
Academic Article Frequency of Parkinsonism and Parkinson Disease in African Americans in the Chicago Community.
Academic Article Systemic brain derived neurotrophic factor but not intestinal barrier integrity is associated with cognitive decline and incident Alzheimer's disease.
Academic Article Novel Variance-Component TWAS method for studying complex human diseases with applications to Alzheimer's dementia.
Academic Article Late-Life Vascular Risk Score in Association With Postmortem Cerebrovascular Disease Brain Pathologies.
Academic Article Disrupted Rest-Activity Rhythms and Cerebral Small Vessel Disease Pathology in Older Adults.
Academic Article Sarcopenia is associated with incident Alzheimer's dementia, mild cognitive impairment, and cognitive decline.
Academic Article Cortical proteins may provide motor resilience in older adults.
Academic Article Objective Assessment of Daytime Napping and Incident Heart Failure in 1140 Community-Dwelling Older Adults: A Prospective, Observational Cohort Study.
Academic Article Association of Lewy Bodies With Age-Related Clinical Characteristics in Black and White Decedents.
Academic Article The association of epigenetic clocks in brain tissue with brain pathologies and common aging phenotypes.
Academic Article Circadian disturbances in Alzheimer's disease progression: a prospective observational cohort study of community-based older adults.
Academic Article Physical activity, brain tissue microstructure, and cognition in older adults.
Academic Article Association of cardiovascular risk burden with risk of dementia and brain pathologies: A population-based cohort study.
Academic Article Latent Cognitive Class at Enrollment Predicts Future Cognitive Trajectories of Decline in a Community Sample of Older Adults.
Academic Article Racial Differences in the Effect of HIV Status on Motor and Pulmonary Function and Mobility Disability in Older Adults.
Academic Article Diverse Motor Performances Are Related to Incident Cognitive Impairment in Community-Dwelling Older Adults.
Academic Article Brain ?-Amyloid Links the Association of Change in Body Mass Index With Cognitive Decline in Community-Dwelling Older Adults.
Academic Article Relationship between objectively measured physical activity on neuropathology and cognitive outcomes in older adults: Resistance versus resilience?
Academic Article Association of White Matter Hyperintensities With Pathology and Progression of Parkinsonism in Aging.
Academic Article Retraction: 24-Hour Rhythms of DNA Methylation and Their Relation with Rhythms of RNA Expression in the Human Dorsolateral Prefrontal Cortex.
Academic Article Microglial Correlates of Late Life Physical Activity: Relationship with Synaptic and Cognitive Aging in Older Adults.
Academic Article Neuropathologic Correlates of Human Cortical Proteins in Alzheimer Disease and Related Dementias.
Academic Article Late-life physical activity relates to brain tissue synaptic integrity markers in older adults.
Academic Article Cortical Proteins and Individual Differences in Cognitive Resilience in Older Adults.
Academic Article Association of Statins With Cerebral Atherosclerosis and Incident Parkinsonism in Older Adults.
Academic Article Daytime napping and Alzheimer's dementia: A potential bidirectional relationship.
Academic Article Mixed Neuropathologies, Neural Motor Resilience and Target Discovery for Therapies of Late-Life Motor Impairment.
Academic Article Higher Dietary Intake of Advanced Glycation End Products Is Associated with Faster Cognitive Decline in Community-Dwelling Older Adults.
Academic Article Proteome-Wide Discovery of Cortical Proteins That May Provide Motor Resilience to Offset the Negative Effects of Pathologies in Older Adults.
Academic Article Influence of Cardiovascular Risk Burden on Motor Function Among Older Adults: Mediating Role of Cardiovascular Diseases Accumulation and Cognitive Decline.
Academic Article Neurodegenerative and Cerebrovascular Brain Pathologies Are Differentially Associated With Declining Grip Strength and Gait In Older Adults.
Academic Article Optimized Glycopeptide Enrichment Method-It Is All About the Sauce.
Academic Article Gait Detection from a Wrist-Worn Sensor Using Machine Learning Methods: A Daily Living Study in Older Adults and People with Parkinson's Disease.
Academic Article Author Response: Association of Statins With Cerebral Atherosclerosis and Incident Parkinsonism in Older Adults.
Academic Article Correlated decline of cognitive and motor phenotypes and ADRD pathologies in old age.
Academic Article Circadian disturbances and frailty risk in older adults: a prospective cohort study.
Academic Article Brain and spinal cord arteriolosclerosis and its associations with cerebrovascular disease risk factors in community-dwelling older adults.
Academic Article Alzheimer's Disease Pathology Outside of the Cerebrum Is Related to a Higher Odds of Dementia.
Academic Article SR-TWAS: Leveraging Multiple Reference Panels to Improve TWAS Power by Ensemble Machine Learning.
Academic Article Effects of Cerebrovascular and Lewy Body Pathology on Parkinsonian Signs in Community-Dwelling Older Adults.
Academic Article Volumetric brain correlates of gait associated with cognitive decline in community-dwelling older adults.
Academic Article A prospective study of the association of cognitive and motor function with odds of life space constriction in older adults.
Academic Article Relation of Motor Impairments to Neuropathologic Changes of Limbic-Predominant Age-Related TDP-43 Encephalopathy in Older Adults.
Academic Article Explainable deep learning approach for extracting cognitive features from hand-drawn images of intersecting pentagons.
Academic Article Dual cognitive and mobility impairments and future dementia - Setting a research agenda.
Academic Article A scalable Bayesian functional GWAS method accounting for multivariate quantitative functional annotations with applications for studying Alzheimer disease.
Academic Article Fragmentation of rest periods, astrocyte activation, and cognitive decline in older adults with and without Alzheimer's disease.
Academic Article Inferring Alzheimer's disease pathologic traits from clinical measures in living adults.
Academic Article Correlates of Person-Specific Rates of Change in Sensor-Derived Physical Activity Metrics of Daily Living in the Rush Memory and Aging Project.
Academic Article Interpretable deep learning approach for extracting cognitive features from hand-drawn images of intersecting pentagons in older adults.
Academic Article Dividing attention during the Timed Up and Go enhances associations of several subtask performances with MCI and cognition.
Academic Article Influence of cardiovascular risk burden on pulmonary function trajectory: role of physical and social activities.
Academic Article Association of AK4 Protein From Stem Cell-Derived Neurons With Cognitive Reserve: An Autopsy Study.
Academic Article Risk Models Based on Non-Cognitive Measures May Identify Presymptomatic Alzheimer's Disease.
Academic Article Differential gene expression analysis based on linear mixed model corrects false positive inflation for studying quantitative traits.
Academic Article Circadian disturbances and frailty risk in older adults.
Academic Article Proteome-wide Analyses Identified Cortical Proteins Associated With Resilience for Varied Cognitive Abilities.
Concept Cognitive Aging
Concept Neuropathology
Concept Machine Learning
Concept ADAMTS Proteins
Concept Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases
Concept Walking Speed
Concept Fitness Trackers
Concept Dietary Approaches To Stop Hypertension
Concept Wearable Electronic Devices
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